Regimen: doxorubicin for axillary lymph node involvement following resection of primary breast cancer in combination with cyclophosphamide

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin

6.5.2.1) Intravenous dose per cycle of Doxorubicin Easy 1


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Regimen : Doxorubicin for axillary lymph node involvement following resection of primary breast cancer in combination with cyclophosphamide.

Cycle: 28 days, repeat every 28 days for 3-5 cycles

  • Doxorubicin, 60 mg/m2, IV bolus, D 1

For doxorubicin calculate total intravenous dose per cycle for a patient measuring 6 feet 1 inches in height and weighing 389 lb.


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lb equals 180.95 mg kg

  • The patient height
    = 6 feet 1 inches
    = ( 6 × 12 + 1 ) inch
    = 73 inch
    = 73 × 2.54 cm
    = 185.42 cm

  • patient weight
    = 389 lb
    = 389 × 0.454 kg
    = 176.6 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 185.42 \quad cm × 176.6 \quad Kg )/(3600)) = 3.0159 ` m2

  • For Doxorubicin :
    `( 60 \quad mg)/( 1 \quad m^2 )` × 3.0159 m2 × 1 (days of treatment)
    = 180.954 mg Ans.

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